Anti-Liver/Kidney Microsomal Antibody
Test Description
The presence of LKM antibodies is used in conjunction with clinical findings and
other laboratory tests to aid in the diagnosis of autoimmune liver diseases such as
autoimmune hepatitis type 2. Autoimmune hepatitis occurs primarily in women and
is associated with very high transaminase levels and elevated gamma globulins,
especially IgG. LKM antibodies are usually evaluated, along with anti-smooth muscle
antibody and antinuclear antibody.
Normal Values
Negative: <20.1 Units
A Possible Meanings of Abnormal Values
Positive
Autoimmune hepatitis type 2
Interventions/Implications
Pretest
• Explain to the patient the purpose of the test and the need for a blood sample to be drawn.
• No fasting is required before the test.
Procedure
• A 7-mL blood sample is drawn in a gold-top (serum separator) collection tube.
• Gloves are worn throughout the procedure
.
Post test
• Apply pressure at venipuncture site. Apply dressing, periodically assessing for continued
bleeding.
• Label the specimen and transport it to the laboratory.
• Report abnormal findings to the primary care provider
.
Clinical Alerts
• Diagnosis of autoimmune hepatitis usually requires liver biopsy.
• Once the diagnosis is confirmed, treatment involving corticosteroids is initiated.
تعليقات
إرسال تعليق